Molecular mechanisms involved in the evolution of genetic code alterations and adaptation of organisms to constitutive stress conditions.
Impact of proteome and genome instability in cell degeneration and aging.
Molecular evolution of proteins and metabolic pathways.
2008 – present: Researcher, IPATIMUP.
2005 – 2008: Post-doctoral fellow, University of Aveiro. Project: mRNA mistranslation in yeast.
2005: PhD in Biology, University of Aveiro. Thesis: Molecular reconstruction of a genetic code alteration.
1999 – 2000: GABBA (Graduated Program in the Areas of Basic and Applied Biology), University of Porto.
1999 – Degree in Biology, University of Aveiro.
2005: Second best poster in MICRO-BIOTEC’05, area of genomics (Lidel Prize).
1998, 1999: Honour Scholarship, to students with exceptional results (University of Aveiro).
1998: Prize Prof. Egas Moniz, best student at the University of Aveiro (Governo Civil de Aveiro).
1997: Prize Dr. Vale Guimarães, best University student from Aveiro (Governo Civil de Aveiro).
2010 – 2013 PTDC/BIA-PRO/099888/2008. Co-evolutionary study of NAD biochemical networks (Principal Investigator).
2010 – 2013 PTDC/AAC-AMB/104532/2008. AMPHIBIA - How will climate changes influence the viability of amphibian populations already stressed with anthropogenic contamination (consultant).
2005 – 2008: POCI/SAU-MMO/55476/2004. Impact of mRNA mistranslation on cell degeneration and evolution (member of team).
2005 – 2008: POCI/BIA-MIC/55466/2004. Unravelling the molecular basis of morphogenesis and mating triggered by a genetic code change in Candida albicans (member of team).
1997 – 1998: Praxis/2/2.1/DC&T/2291/95. EPANAFORA – educate to promote new attitudes towards the environment (member of team).
Jun – Jul 2006: Sir William Dunn School of Pathology, University of Oxford, UK.
Oct – Dec 2003: Genomics Lab, University Medical Centre, Utrecht, The Netherlands (supported by an EMBO short-term fellowship).
Jan – Apr 2001 and Feb – Jul 2002: Institut de Biochimie et Génétique Cellulaires du CNRS, Bordeaux, France.
Jul 2000: Departamento de Microbiología II de la Facultad de Farmacia, Universidad Complutense de Madrid, Spain.
2011: Tales from a NAD world. CIIMAR invited seminar, Porto, Portugal.
2009: Evolution through proteome destabilization. 12th Portugaliae Genetica, Porto, Portugal.
2006: The role of mRNA mistranslation on cell degeneration and aging. XV National Congress of Biochemistry, Aveiro, Portugal.
2004: A proteomics approach to mRNA mistranslation in Saccharomyces cerevisiae. Congrès de la Societé Française d’Electrophorèse et d’Analyse Proteomique, Bordeaux, France.
2002: A functional genomics approach to the evolution of alternative genetic codes. XIII Congresso Nacional de Bioquímica, Lisboa, Portugal.